Acitrin Tablet: Each tablet contains Cetirizine Dihydrochloride BP 10 mg.
Acitrin Syrup: Each 5 ml syrup contains Cetirizine Dihydrochloride BP 5 mg.
Acitrin Paediatric Drops: Each ml contains Cetirizine Dihydrochloride BP 2.5 mg.
Acitrin ® is a preparation of Cetirizine dihydrochloride. It is a piperazine derivative and metabolite of Hydroxyzine, which is long acting and has some mast-cell stabilizing activity. Principal actions of Cetirizine are mediated by selective inhibition of peripheral H 1 -receptors.
Route: Oral
Adults and children ≥6 years:
Children 2 to 6 years:
Children 6 months to <2 years:
Renal & Hepatic impairment:
In decreased renal function (CrCl 11–31 mL/min), hemodialysis (<7 mL/min), or hepatic impairment: 1/2 tablet or 1 teaspoonful once daily.
Alcohol and CNS depressants potentiate central nervous system depression and psychomotor impairment; theophylline marginally decreases cetirizine clearance.
Cetirizine Dihydrochloride is contraindicated in those patients with a known hypersensitivity to it or any of its ingredients or hydroxyzine.
Common: Sedation, headache, dry mouth, gastrointestinal disturbances.
Overdose
Only limited information is available regarding overdosage in humans although the most likely effect of overdosage is hypotension. If overdosage is occurred, the patient should be carefully monitored and treatment should be symptomatic and supportive.
Category B. There are no adequate and well-controlled studies in pregnant women; use during pregnancy only if clearly needed. Lactation: Cetirizine is excreted in human breast milk; use in nursing mothers is not recommended.
Store below 30°C in a cool, dry place. Protect from light and moisture. Keep out of reach of children.