Syrup: Each 5 ml contains Ambroxol Hydrochloride BP 15 mg.
Paediatric Drops: Each ml of drop contains Ambroxol Hydrochloride BP 6 mg.
Ambroxol is the active metabolite of Bromhexine and it has been proven that this metabolite possesses a greater bronchosecretory effect than Bromhexine. It improves sputum rheology by hydrating mechanism leading to liquefaction of mucus in the lumen of respiratory tract, thus facilitating expectoration of mucus and reducing dyspnea. It stimulates production of phospholipids of surfactant by alveolar cells, thus contributing to the lowering of superficial tension in the alveoli. It also reduces bronchial hyperactivity. X-COLD (Ambroxol) has anti-inflammatory properties owing to the inhibitory effect on the production of cellular cytokines and arachidonic acid metabolites. In patients with COPD it traditionally improves airway patency.
Route of administration: Oral.
Average daily dose (preferably after meal):
OR AS DIRECTED BY THE PHYSICIAN.
With medicine: May increase the concentrations of antibiotics (e.g. Cefuroxime, Doxycycline, Erythromycin, Amoxicillin) in the lung tissue.
With food & others: There is no data found on interaction with food and others.
Overdose:Symptoms and signs: Manifestations of poisoning are so far unknown in humans.
Treatment: Symptomatic treatment is recommended.
Age and gender do not affect the pharmacokinetics of ambroxol; therefore adjustment of the dose is unnecessary.
Ambroxol should be given cautiously to patients with gastric and duodenal ulceration or convulsive disorders. Patients with hepatic and renal insufficiency should take it with caution.
Keep all medicines out of reach of children.
Store below 30°C, protected from light.