VeterinaryAnthelmintics

Trilev-Vet®

Bolus
600 mg + 900 mg
GENERIC NAMELevamisole + Triclabendazole
MANUFACTURED BYSquare Pharmaceuticals PLC
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Available Pack Sizes:1 Size
Purchase Option:Full Pack
Maximum Retail Price (MRP):
Quantity
৳ 451.43/ 5 x 4
1
(Unit: ৳ 22.57 / 1 Bolus)
16263

Composition

Each bolus contains Triclabendazole INN 900 mg and Levamisole BP 600 mg equivalent to Levamisole HCl BP 708 mg.

Description

Trilev-Vet combines two active pharmaceutical ingredients with complementary mechanisms of action. Levamisole acts as a cholinergic agent that stimulates ganglia and depolarizes parasite muscle tissue. This dual effect induces muscular paralysis, preventing the worms from maintaining their station in the host gut, leading to their subsequent expulsion. Triclabendazole, a benzimidazole derivative, is highly effective against all developmental stages of liver flukes, ranging from 1-day-old immature forms to adults. Benzimidazoles bind to beta-tubulin, a critical structural protein, thereby blocking the polymerization of tubulin into microtubules. This disruption compromises cellular integrity and essential transport functions within the parasite, ultimately resulting in parasite death.

Indications

Livestock:

Trilev-Vet is indicated as a broad-spectrum anthelmintic for the treatment of helminth infestations in cattle, buffalo, sheep, and goats.
The formulation is utilized for the treatment of acute, sub-acute, and chronic fascioliasis caused by early immature, immature, and adult stages of *Fasciola hepatica* and *Fasciola gigantica*.
It is additionally effective against major ruminant parasites including *Haemonchus* and *Ostertagia* of the abomasum.
The drug also targets *Cooperia*, *Trichostrongylus*, and *Bunostomum* of the small intestine.
Furthermore, it eliminates *Oesophagostomum* and *Trichuris* of the large intestine, as well as *Dictyocaulus* species of the lungs.
The preparation is successful in treating eye worms (*Thelazia*) in cattle.
The formulation eradicates all types of larvae, immature and mature flukes, and worms.
It exhibits no embryotoxic or teratogenic effects.
The treatment utilizes a single-dose therapy for ease of use, saving time and money.
Administration ensures increased body weight and milk production.
The product is safe for use during pregnancy and lactation.

Dosage & Administration

Route of Administration: Oral (dissolved in water as drench, or mixed with feed/molasses, or in banana leaf).

Livestock: 195 mg per kg body weight (1 bolus per 75 kg body weight).
10–20 kg: ¼ bolus.
21–40 kg: ½ bolus.
41–75 kg: 1 bolus.
76–150 kg: 2 boluses.
151–225 kg: 3 boluses.
226–300 kg: 4 boluses.
301–375 kg: 5 boluses.
376–450 kg: 6 boluses.

Or as directed by a registered veterinary doctor.

Contraindications

Trilev Vet bolus is contraindicated in animals hypersensitive to active ingredients.

Side Effects

Trilev Vet bolus is well tolerated by the animals. At the recommended doses, side effects are relatively nil.

Withdrawal Period

Meat: 28 days and Milk: 10 days must not be consumed after administration.

Trilev-Vet® • 5 x 4
৳ 451.43