Bisocor® 2.5 Tablet: Each film coated tablet contains Bisoprolol Fumarate USP 2.5 mg.
Bisocor® 5 Tablet: Each film coated tablet contains Bisoprolol Fumarate USP 5 mg.
Bisoprolol blocks the action of the sympathetic nervous system on the heart by blocking the heart’s $b_1$-adrenergic receptors. Bisoprolol reduces the heart rate & force of contraction of the heart, thus lowers blood pressure.
Bisocor® (Bisoprolol) is indicated in the management of hypertension and in the treatment of angina. It may be used alone or in combination with other antihypertensive agents.
The dose of Bisocor® must be individualized to the needs of the patient. The usual starting dose is Bisocor® 5 mg once daily. In some patients, Bisocor® 2.5 mg may be an appropriate starting dose. If the antihypertensive effect of Bisocor® 5 mg is inadequate, the dose may be increased to Bisocor® 10 mg and then, if necessary, to 20 mg once daily. Patients with Renal or Hepatic Impairment: In patients with hepatic impairment (hepatitis or cirrhosis) or renal dysfunction (creatinine clearance <40 mL/min), the initial daily dose should be 2.5 mg and caution should be used in dose-titration. Geriatric Patients: It is not necessary to adjust the dose in the elderly, unless there is also significant renal or hepatic dysfunction. Pediatric Patients: There is no pediatric experience with Bisoprolol.
Pregnancy: Bisoprolol should not be used during pregnancy unless clearly necessary. If treatment with Bisoprolol is considered necessary, the uteroplacental blood flow and the foetal growth should be monitored. Lactation: It is not known whether this drug is excreted in human milk. Therefore, breast-feeding is not recommended during administration of Bisoprolol.
Impaired renal or hepatic function: Use caution in adjusting the dose of Bisoprolol in patients with renal or hepatic impairment. Risk of anaphylactic reaction: While taking beta-blockers, patients with a history of severe anaphylactic reaction to a variety of allergens may be more reactive to repeated challenge, accidental, diagnostic or therapeutic. Such patients may be unresponsive to the usual doses of epinephrine used to treat allergic reaction.
Overdosage:
The most common signs expected with overdosage of a beta-blocker are bradycardia, hypotension, congestive heart failure, bronchospasm, and hypoglycemia. Only a few cases of overdose with Bisoprolol have been reported. Storage: Keep out of the reach of children. Protect from light and moisture, keep in a cool and dry place.
How supplied:
Bisocor® 2.5 Tablet: Each box contains 50 tablets in blister pack. Bisocor® 5 Tablet: Each box contains 30 tablets in blister pack.