Ace® Plus Tablet: Each tablet contains Paracetamol BP 500 mg & Caffeine BP 65 mg.
Ace® Plus is the combination of Paracetamol (Acetaminophen) and Caffeine. It has analgesic and antipyretic properties. The presence of Caffeine increases the analgesic effect of Paracetamol. Paracetamol is one of the safest and most widely used analgesic and antipyretic. It produces analgesic action by elevation of the pain threshold and antipyresis through action on the hypothalamic heat regulating center. Caffeine is an alkaloid which is a theophylline like Xanthine derivative. By intermolecular association with Paracetamol, Caffeine increases the solubility and transmembrane permeation of Paracetamol. In addition caffeine increases the pain threshold and tolerance of pain. Caffeine has also an intrinsic power to raise vessel tone in the cranial of the brain, which provides another benefit to treat migraine and headache.
Fever, headache, migraine, muscle ache, backache, toothache & menstrual pain.
Adults: 1-2 tablets every 4-6 hours. Maximum dose: 8 tablets daily. Not recommended for children below 12 years.
It increases the effect of chloramphenicol and coumarin anticoagulant. Risk of hepatotoxicity of paracetamol may be increased in alcoholics or in patients taking other anti-epileptic medications.
Should be given cautiously in the following cases:
Prolonged use of the drug without consulting a physician should be avoided.
Store in a cool and dry place, protect from light and moisture. Keep all medicines out of the reach of the children.