Ridon® FCT: Each film-coated tablet contains Domperidone maleate BP equivalent to 10 mg Domperidone.
Ridon® Suspension: Each 5 ml suspension contains Domperidone BP 5 mg.
Ridon® Paediatric Drops: Each 1 ml drop contains Domperidone BP 5 mg.
RIDON FAST® Tablet: Box.
Ridon® is a preparation of Domperidone. It is a dopamine antagonist with anti-emetic properties. Domperidone does not readily cross the blood-brain barrier. In Domperidone users, especially in adults, extrapyramidal side effects are very rare, but Domperidone promotes the release of prolactin from the pituitary gland. Its anti-emetic effect may be due to a combination of peripheral (gastrokinetic) effects and antagonism of dopamine receptors in the chemoreceptor trigger zone.
Adults: 10-20 mg (1-2 tablet or 10-20 mL suspension or 1-2 sachets) 3 to 4 times daily, before meal.
Children: Nausea and vomiting following cytotoxic therapy or radiotherapy only; 200-400 µgm / Kg (2-4mL suspension / 10 Kg or 0.4-0.8 mL drops / 10 Kg) body weight 3 to 4 times daily.
(Ridon® should be taken 15-30 minutes before meal. Maximum period of treatment is 12 weeks.).
Use in pregnancy: The potential risk of Domperidone in pregnant women is unknown. Therefore, Ridon® should only be used during pregnancy when justified by the anticipated therapeutic benefit.
Use in lactating mother: Domperidone concentrations in breast milk of lactating women are 10 to 50% of the corresponding plasma concentrations and expected not to exceed 10 ng/mL. The total amount of Domperidone excreted in human breast milk is expected to be less than 7µg per day at the highest recommended dosing regimen. It is not known whether this is harmful to the newborn. Therefore breast-feeding is not recommended for mothers who are taking Domperidone.
Overdose:
Symptoms of overdosage may include drowsiness, disorientation and extrapyramidal reactions, especially in children. There is no specific antidote to Domperidone, but in the event of overdose, gastric lavage as well as the administration of activated charcoal, may be useful. Close medical supervision and supportive therapy is recommended. Anticholinergic, anti-parkinson drugs may be helpful in controlling the extrapyramidal reactions.
Keep away from light and wet place. Store at or below 30°C temperature. Keep out of reach of children.