Each tablet contains Loratadine INN 10 mg.
Pretin is a potent, rapidly effective and long-acting non-sedative, histamine Hâ‚ receptor antagonist, with anti-allergic properties. Each Pretin tablet contains 10 mg of Loratadine INN.
Pretin is indicated for.:
Adult and children above 12 years of age: 10 mg (1 Pretin tablet) once-a-day.
Children
Safety and efficacy of Loratadine in children below 2 years of age have not yet been established.
There are no reports of potentially hazardous interactions with other drugs to date. Psychomotor performance studies show that unlike other Hâ‚-receptor antagonists, loratadine does not potentiate the effect of alcohol when administered concomitantly with it.
The lack of sedation by loratadine was further confirmed by special psychomotor studies such as the driving performance test.
Neonates: The drug is not normally used in neonates.
Lactating mothers: Like other Hâ‚ receptor antagonists, loratadine is also excreted in breast milk. So lactating mothers are advised not to take the drug.
Children: There are no special precautions required for young children over 2 years. But the safety and efficacy of loratadine in children below 2 years of age have not yet been established.
Pregnant women: Although loratadine was not found to be teratogenic in animals, but the safe use of loratadine during pregnancy has not been established and there have been no case reports of any adverse foetal consequences. So it should be used only if the potential benefit justifies the potential risk to the foetus.