Politrim Vet

Each bolus contains Sulfamethoxazole BP 1000 mg and Trimethoprim BP 200 mg.

Politrim Vet contains a combination of sulfamethoxazole and trimethoprim, which exhibits a synergistic antimicrobial effect. Sulfamethoxazole is a broad-spectrum sulfonamide antibiotic that inhibits bacterial DNA synthesis by blocking the dihydrofolate synthetase enzyme. Trimethoprim complements this activity by inhibiting bacterial DNA synthesis through the blockade of the dihydrofolate reductase enzyme.

Livestock:

Route of Administration: For oral administration only.

Or as directed by the Registered Veterinary Physician.

With medicine: Local anesthetics of the group of para aminobenzoic esters (procain, tetracain) may inhibit the activity of sulfadimidine locally. Hexamethylenetetramine (methenamine) must not be given concomitantly with sulfadimidine, as a loss in activity and crystalluria may occur. No interaction known with feed or food.

Contraindicated in animals hypersensitive to sulfonamides and/or trimethoprim and birds with known liver/kidney problems.

Common side effects: Occasionally, crystalluria, hematuria, and renal tubule obstruction may occur. Rare side effects: Precipitate in the urine, particularly when given at high dosages for prolonged periods.

This medicine may cause fetal harm if used during pregnancy.

This combination should be used with caution in animals with renal/hepatic disease.

Store below 30°C in a dry place. Keep all medicines out of reach of children.

Meat: 12 days and Milk: 4 days must not be consumed after administration.