Proventa® 100 mg HFA Inhaler: Each actuation delivers 100 mg of Salbutamol. It does not contain any other ingredients.
Salbutamol BIF is the active ingredient of Proventa® Inhaler. It is a 50% controlled-release tablet designed to be used in the treatment of asthma and other forms of diffuse inflammatory disease.
Mode of action:
Salbutamol is a selective adrenergic agonist and is a potent bronchodilator. It is a potent bronchodilator and is a potent bronchodilator. It is a potent bronchodilator and is a potent bronchodilator. It is a potent bronchodilator and is a potent bronchodilator.
Pharmacokinetics:
Following inhalation, salbutamol is rapidly and completely absorbed into the blood. After 1 to 2 hours, the concentration of the drug is undetectable. The portion of the dose which is swallowed and absorbed by the respiratory tract is approximately 10% of the total dose. Salbutamol is not metabolized in the lung but is excreted in the urine. A 50% controlled-release tablet is metabolized by oxidative deamination and conjugation with glucuronide. Salbutamol is ultimately excreted in the urine as free drug and as the metabolite.
Proventa® (Salbutamol) Inhaler is indicated for the treatment of severe asthma and the treatment of reversible bronchial asthma in patients with chronic obstructive pulmonary emphysema. Proventa® Inhaler may be used to relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute bronchitis and may also relieve attacks of acute.
Adults For the relief of acute bronchospasm and for managing intermittent episodes of asthma: 1 or 2 inhalation as a single dose For chronic maintenance or prophylactic therapy: 2 inhalations three or four times daily prevention of exercise induced bronchospasm: 2 inhalations before exertion.
Children:
For relief of acute bronchospasm, management of episodic asthma and for prevention of exercise induced bronchospasm: 1 inhalation; for routine maintenance and prophylaxis: 1 inhalation three or four times daily, increasing if necessary to 2 inhalations three or four times daily. Elderly The dosage is the same as that for adults.
No potentially hazardous interactions have been reported, but treatment with diuretics may augment the hypokalemia that occurs with large doses of salbutamol.
Over dosage An overdose of Salbutamol can be fatal. Overdose symptoms may include nervousness, headache, tremor, dry mouth, chest pain or heavy feeling, rapid or uneven heart rate, pain spreading to the arm or shoulder, nausea, sweating, dizziness, seizure (convulsions), light-headed or fainting.
, Salbutamol inhaler preparations are not appropriate for managing premature labour. It should not be used for threatened abortion during the first or second trimesters of pregnancy. Salbutamol inhaler is contraindicated in patients with a history of hypersensitivity to any of its components.
Pregnancy Category C: level of Salbutamol Sulphate and HFA-134a after inhaled therapeutic doses are very low in humans but it is not known whether the of Salbutamol HFA excreted in human milk.
In the event of previously effective dose of Salbutamol inhaler failing to give relief for at least three hours, the patient should be advised to seek medical advice in order that any necessary additional steps may be taken. It should be administered cautiously to patients suffering from thyrotoxicosis. As with other inhalation therapy, the potential for paradoxical bronchospasm should be kept in mind. If it occurs, the preparation should be discontinued immediately and alternative therapy should be instituted.
Pressurised canister, do not puncture, break or incinerate even when apparently empty. Avoid storage in direct sunlight or heat. Store below 30 C. Keep away from eyes. Keep away from children.
CABICAT AT Manufactured by Opsonin Pharma Limited Opsonin Pharma Rupatali, Barishal, Bangladesh. Registered Trade Mark.
Keep out of reach of children. Store in a dry place, below 30 C temperature and protected from light.