Finix 20 mg Tablet: Each enteric coated tablet contains Rabeprazole Sodium BP 20 mg.
Finix 10 mg Capsule: Each delayed release sprinkle capsule contains Rabeprazole Sodium BP 10 mg.
Finix 20 mg Capsule: Each delayed release capsule contains Rabeprazole Sodium BP 20 mg.
Rabeprazole Sodium (Finix ) is an antiulcerant drug in the class of Proton Pump Inhibitor.
Pharmacokinetics:
Rabeprazole suppresses gastric acid secretion by inhibiting the gastric H*/K*-ATPase enzyme at the secretory surface of the gastric parietal cell. Rabeprazole is absorbed and can be detected in plasma by 1 hour. The effects of food on the absorption of Rabeprazole have not been evaluated. Rabeprazole is 96.3% bound to human plasma proteins. Approximately 90% of Rabeprazole is eliminated in the urine. The remainder of the dose is excreted in the feces.
Dosage &:
Treatment duration Frequency.
Disease.
Healing of erosive or ulcerative 99 mg 4 to 8 weeks; patients have not healed after Esophageal Reflux Disease (GERD) 8 weeks of treatment, an additional 8 week.
once daily course may be considered.
Maintenance of healing of erosive 20mg ulcerative GERD once daily.
Treatment of Symptomatic GERD 20 mg 4 weeks; If symptoms do not resolve once daily completely after 4 weeks, an additional course of treatment may be considered.
Healing of Duodenal Ulcer 20 mg 4 weeks; If symptoms do not resolve once daily completely after 4 weeks, an additional course of treatment may be considered.
Treatment of Pathological 60mg Doses should be adjusted to individual secretory Conditions, including once daily patient needs and should continue for as Zollinger-Ellison Syndrome long as clinically indicated.
Treatment of GERD in pediatric patients 5mg 12 weeks with the option to increase to 1 to 11 years of age (Less than 15 kg) once daily 10 mg if inadequate response.
Treatment of GERD in pediatric patients 10mg 12 weeks. 1 to 11 years of age (15 kg or more) once daily.
Helicobacter pylori Eradication to Reduce the Risk of Duodenal Ulcer Recurrence:
Drug Dose Duration Rabeprazole Sodium 20 mg Twice Daily for 7 Days Amoxicillin 1000 mg Twice Daily for 7 Days Clarithromycin 500 mg Twice Daily for 7 Days *All three medications should be taken twice daily with the morning and evening meals.
Rabeprazole is metabolized by the Cytochrome P-450 (CYP-450) drug metabolizing enzyme system. Rabeprazole does not have clinically significant interactions with other drugs metabolized by the CYP-450 system, such as Warfarin, Theophylline, Diazepam and Phenytoin etc.
Over dosage: There has been no experience with large overdoses with Rabeprazole. In the event of overdosage, treatment should be symptomatic and supportive.
Rabeprazole should be used in pregnancy only if the potential benefit justifies the potential risk to the fetus. There are no data on the excretion of Rabeprazole into the breast milk. But due to many medicine excreted through the breast milk, so precaution must be taken during lactation period.
Administration of Rabeprazole Sodium to patients with mild to moderate liver impairment resulted in increased exposure and decreased elimination. Caution should be exercised in patients with severe hepatic impairment.
Keep out of reach of children. Store in a dry place, below 25 C temperature and protected from light.