Flamex Gel: Each gram gel contains Ibuprofen BP 50 mg.
Flamex® Gel is the preparation of Ibuprofen which is a phenylpropionic acid derivative which exerts its anti-inflammatory and analgesic effects directly in inflamed tissues underlying the site of application, mainly by inhibiting prostaglandin biosynthesis. Because it is formulated in an aqueous or alcoholic gel, the preparation also exerts a soothing and cooling effect when applied to the affected area.
Route of administration: Flamex® Gel is for topical use only. Do not take by mouth.
Adults and children over 14 years: Apply Flamex® Gel up to 3 times a day but no more. Do not use more often than every 4 hours. Always try on a small area first. Use 1 cm to 4 cm each time when using Flamex® Gel. Apply the gel as a thin layer over the affected area. Gently rub the gel until it is absorbed. If the pain or swelling continues after using the gel for 2 weeks, consult with physician.
Topical absorption is minimal; caution when used concurrently with oral NSAIDs or anticoagulants due to additive systemic anti-inflammatory effects.
Ibuprofen is contraindicated in patients with known hypersensitivity to ibuprofen, aspirin or other non-steroidal anti-inflammatory drugs or any components of this product. It is also contraindicated in patients with asthma, rhinitis, itching or rashes.
Common: Blisters, skin rash, itching, erythema, localized bruising. Less Common: Wheezing, shortness of breath, facial swelling.
Overdose
Overdose with a topical presentation of ibuprofen gel is unlikely. Symptoms of severe ibuprofen overdose (e.g., following accidental oral ingestion) include headache, vomiting, drowsiness and hypotension. Correction of severe electrolyte abnormalities should be considered.
Category C (1st/2nd trimesters), Category D (3rd trimester). Do not use if more than 6 months pregnant due to systemic prostaglandin inhibition. Lactation: Avoid topical application to breast area while nursing.
Store below 25°C in a cool, dry place. Protect from light and heat. Do not freeze. Keep out of reach of children.