Curin® Tablet: Each film coated tablet contains Levocetirizine Dihydrochloride INN 5 mg.
Curin tablet is a preparation of Levocetrizine Dihydrochloride. Levocetrizine is the active (levo) isomer of Cetrizine. It is a new highly effective and well tolerated non-sedating antihistamine with potent antiallergic properties. It has a two fold higher affinity for Hâ‚ receptors than Cetrizine. Levocetrizine has a rapid and long lasting action, allowing once a day administration.
Adults & children over 6 years of age: One Curin tablet (Levocetrizine Dihydrochloride 5 mg) once daily.
Patients with renal impairment: The recommended dose in patients with moderate renal impairment is one Curin tablet every two days. In those with sever renal impairment, the dose interval should be increased to every three days. Patients with end stage renal disease should not be given Levocetrizine.
Generally Levocetrizine is well tolerated. However, a few side effects like headache, dry mouth, fatigue and skin rash have been reported rarely.
The safety of Levocetrizine in pregnancy has not been established. Therefore, it should be used with caution during pregnancy and only if the potential benefits to the mother outweigh any risks to the foetus.
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THERAPEUTIC INDEX
Lactation: Levocetirizine passes into breast milk. So, it should be used with caution in nursing mothers and only if the expected benefit to the mother is greater than the risk to the nursing infant.
Paediatric use: Not recommended for use in children less than 6 years of age.