Clobex® Capsule: Each capsule contains Cloxacillin Sodium BP equivalent to 500 mg Cloxacillin.
Clobex® Syrup: After reconstitution each 5 ml contains Cloxacillin Sodium BP equivalent to 125 mg Cloxacillin.
Clobex (Cloxacillin) is a β lactamase resistant antibacterial agent with bactericidal activity against most Gram-positive organisms and Neisseria spp. It is also effective against β lactamase producing Gram-negative organisms when given with Ampicillin.
Clobex is indicated for the treatment of infections caused by Gram-positive organisms including infections caused by β lactamase producing Staphylococci such as.:
Dose may be doubled in severe infection and should be taken at least 30 minutes before food.
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THERAPEUTIC INDEX
Common side effects are skin rash, transient diarrhoea, nausea, heartburn, pruritus and disturbance of blood electrolyte. Rarely anaphylactic shock.
Clobex should be given with caution to patients with known history of allergy.