Brodil HFA Inhaler: Each canister contains 200 measured doses, each containing 100 micrograms of Salbutamol BP.
Brodil HFA inhaler is a preparation of Salbutamol Sulphate which is CFC free inhaler Salbutamol is a relatively selective ß2 adrenoreceptor stimulant. It is more specific than both isoprenaline and orciprenaline for adrenergic ß2 receptors. Mechanism of action : Brodil HFA is a sympathomimetic agent which has a highly selective action on ß adrenergic receptors in bronchial muscle. It provides short acting (4 to 6 hours) bronchodilation with fast onset (within 5 minutes) in reversible airway obstruction. ß2 adrenoreceptor agonist is used in the treatment of asthma and other forms of diffuse reversible airways obstruction.
Route of administration : Brodil HFA inhaler is administered by the inhaled route only. Shake Brodil HFA inhaler well before each spray.
Adults For the relief of acute bronchospasm and for managing intermittent episodes of asthma: One or two puffs as single dose.
For chronic maintenance or prophylactic therapy: Two puffs three or four times daily.
For prevention of exercise induced bronchospasm: Two puffs should be taken at least 15 minutes before exertion.
Children For the relief of acute bronchospasm, management of episodic asthma and for prevention of exercise induced bronchospasm: One puff may be administered as single dose.
For routine maintenance and prophylaxis: One puff three or four times daily, increasing if necessary to two puffs three or four times daily.
Elderly The dosage is the same as that for adults.
Beta-adrenergic receptor blocking agents antagonize salbutamol efficacy; diuretics increase hypokalemic risk; sympathomimetics potentiate cardiovascular toxicity; cardiovascular effects enhanced by MAOIs and tricyclic antidepressants.
Salbutamol inhaler is contraindicated in patient with known hypersensitivity to salbutamol or any components of this product. Inhaler preparations are not appropriate for managing premature labour.
Less Common: Tremor, headache. Rare: Muscle cramps, angioedema, urticaria, bronchospasm, hypotension, paradoxical bronchospasm.
Overdose
As with all sympathomimetic aerosol medications, cardiac arrest and even death may be associated with abuse. The preferred antidote for overdose with salbutamol inhaler is cardioselective ß-blocker, such as metoprolol tartarate. But ß -blockers should be used with caution in patients with a history of bronchospasm. Dialysis is not appropriate treatment for overdose of salbutamol inhalation aerosol.
Category C. Crosses the placenta; use during pregnancy only if expected benefit outweighs fetal risk. Lactation: Probably excreted in human milk; use in nursing mothers is not recommended.
Store below 30°C. Protect from direct sunlight and heat. Do not puncture or incinerate canister. Keep away from eyes and children.