Each gm cream contains methyl salicylate BP 150 mg & menthol BP 100 mg.
Methyl salicylate is a salicylic acid derivative. Salicylates inhibit cyclooxygenase, thereby reducing the formation of prostaglandins, and cause platelet dysfunction. Methyl salicylate is used topically as a counter-irritant. Upon application, it is absorbed through the skin and is applied for the relief of pain in rheumatic conditions and painful muscle or joints. Menthol dilates the blood vessels causing a sensation of coldness, followed by an analgesic effect. Menthol also acts as a penetration enhancer, increasing the penetration of drugs when applied on the skin, to give a faster onset of action.
Adults including elder: Apply to the affected area 2-3 times daily, maximum 4 times in a day.
It is used topically so no interaction with other drugs.
Allergy to salicylate or sensitivity to any of the components. Application to broken skin or raw surfaces is contraindicated.
Common: Generally well tolerated but may cause skin irritation at the application site.
Rare: Redness or irritation may occur, especially in persons with sensitive skin.
Overdose
Large amount of topical application may cause salicylism (symptoms of salicylism include tinnitus, hearing loss, nausea, vomiting etc).
This medication should be used only if clearly needed during pregnancy or while breast-feeding.
Keep away from eyes, mucous membranes, wounds or damaged skin. If skin irritation develops discontinue use of this cream. Do not swallow. It should not be used immediately after bath.