Each 5 ml contains Dextromethorphan Hydrobromide BP 20 mg, Phenylephrine Hydrochloride BP 10 mg and Triprolidine Hydrochloride BP 2.5 mg.
Dextromethorphan Hydrobromide is a cough suppressant used to treat coughing. Phenylephrine Hydrochloride stimulates postsynaptic alpha-receptors, resulting in vasoconstriction, which reduces nasal congestion. Triprolidine Hydrochloride is a sedating antihistamine which is used for the symptomatic relief from allergic rhinitis.
Temporarily relieves these symptoms due to common cold, hay fever (allergic rhinitis) or other upper respiratory allergies:
Route of Administration: Oral.
Adults & Children 12 years of age and older: 1 teaspoonful (5 ml) every 4 hours.
Children 6 to under 12 years age: ½ teaspoonful (2.5 ml) every 4 hours.
Or as directed by the physician.
With medicine: Taking certain MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid taking isocarboxazid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, or tranylcypromine during treatment with this medication. Most MAO inhibitors should also not be taken for two weeks before treatment with this medication. Caution should be exercised while taking this drug with antihistamines applied to the skin (such as diphenhydramine cream, ointment, spray), antispasmodics (e.g. atropine, belladonna alkaloids), beta blockers (e.g. metoprolol, atenolol), drugs for Parkinson’s disease (e.g. anticholinergics such as benztropine, trihexyphenidyl), guanethidine, certain inhaled anesthetics (e.g. halothane), methyldopa, reserpine, scopolamine, tricyclic antidepressants (e.g. amitriptyline, desipramine), anti-seizure drugs (e.g. carbamazepine), medicine for sleep or anxiety (e.g. alprazolam, diazepam, zolpidem), muscle relaxants, narcotic pain relievers (e.g. codeine), psychiatric medicines (e.g. chlorpromazine, risperidone, amitriptyline, trazodone).
With food and others: There is no data found on interaction with food of this medicine.
Over dosage:
In cases of over dosage, hospital admission is strongly advised. Over dosage may produce respiratory depression, paranoid psychosis, delusions.
There are no specific data on use of this combination during pregnancy and lactation.
Not to be used in children below 2 years old. To be used with caution, and as advised by the physician for children age 2 to 6 years.
As with other sympathomimetic agents, caution should be exercised in patients with hypertension, heart disease, diabetes, thyroid disease or glaucoma. This combination should not be used for persistent or chronic cough which occurs with smoking, asthma, chronic bronchitis or for a cough with excessive secretion of phlegm unless directed by a physician. Precaution should be taken for persons with trouble urinating due to an enlarged prostate gland.
This combination may impair the patients ability to drive and also to operate machinery.